If it’s not possible to bring your dog along on your vacation, you’ll have to arrange for his care while you’re away. One choice is to have a reliable person come to your home several times a day to feed, water, exercise, and spend time with your dog. You could always hire a professional pet-sitter, these services are springing up in many places. This however is a whole separate topic. You would need lots of references before you could trust someone to come and spend so much time with your pet.
Another consideration is that dogs have a tendency to “look” for their masters. So make sure that your dog will not be able to escape to find you, wherever you chose to keep your dog. Dogs can be great escape artists, and will practically do anything to look for their masters.